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Germ-free animal : ウィキペディア英語版 | Germ-free animal Germ-free animals are animals that have no microorganisms living in or on it. Such animals are raised within germ-free isolators in order to control their exposure to viral, bacterial or parasitic agents.〔(University of Michigan ) Germ Free Animal Facility - example facility for raising germ-free animals〕 When known strains of bacteria or microbiota are introduced to a germ-free animal, it usually referred to as a gnotobiotic animal, however technically speaking, germ-free animals are also gnotobiotic because the status of their microbial community is ''known''.〔Reyniers, J.A. (Germfree Vertebrates: Present Status ) (1959) ''Annals of the New York Academy of Sciences.'' 78(1):3.〕 Germ-free animals are used in the study of probiotic research and other animal research requiring careful control of outside contaminants that can affect the experiment.〔(Of Probiotics and Possibilities ) - J. Armbrecht. Dept of Bacteriology, University of Wisconsin-Madison. August 2, 2000.〕 == References == 〔
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